Significant Allergic Reactions. Promethazine/phenylephrine/codeine may possibly induce allergic reactions, that may be serious. End using promethazine/phenylephrine/codeine and acquire aid immediately Should you have any of the subsequent indications of a significant allergic response.

There may be other side effects of promethazine/phenylephrine/codeine that are not outlined right here. Make contact with your healthcare provider if you're thinking that you happen to be having a facet effect of a medication.

Concomitant administration of promethazine goods with other respiratory depressants has an association with respiratory depression, and at times Loss of life, in pediatric sufferers.

Promethazine hydrochloride occurs as a white to faint yellow, virtually odorless, crystalline powder which slowly but surely oxidizes and turns blue on prolonged exposure to air.

Clients needs to be suggested to evaluate Promethazine with Codeine Oral Solution with an correct measuring device. A household teaspoon is not really an precise measuring unit and may lead to overdosage, especially when a half a teaspoon is calculated. A pharmacist can endorse an proper measuring product and can offer Guidance for measuring the correct dose. Promethazine and codeine could trigger marked drowsiness or could impair the psychological and/or Actual physical skills required for the efficiency of potentially hazardous responsibilities, such as driving a car or truck or operating machinery.

For those who have been having promethazine/phenylephrine/codeine on a regular basis, tend not to halt taking the medication with out talking to your Health care supplier. Halting also quickly may perhaps lead to really serious Unwanted effects. Simply call your Health care provider at once if you have any of the following signs and symptoms. 

Codeine: In patients receiving MAO inhibitors, an Original little examination dose is a good idea to allow observation of any extreme narcotic outcomes or MAOI interaction.

Though specific medicines shouldn't be made use of alongside one another in any way, in other scenarios two diverse medicines may be made use of collectively although an conversation may manifest. In these cases, your medical doctor will want to change the dose, or other safeguards can be needed.

Should you be taking codeine to suppress your cough, there read more are lots of other medicines offered around-the-counter in a pharmacy. Speak to your health practitioner or pharmacist about what may be an acceptable option for you.

Promethazine: Promethazine can be a phenothiazine by-product which differs structurally in the antipsychotic phenothiazines because of the presence of a branched aspect chain and no ring substitution. It is believed this configuration is answerable for its relative deficiency (1/10 that of chlorpromazine) of dopamine antagonist Homes. Promethazine is definitely an H one receptor blocking agent. Along with its antihistaminic action, it provides clinically useful sedative and antiemetic outcomes.

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In One more review just one 100-mg/ kg dose of codeine administered to Expecting mice reportedly resulted in delayed ossification while in the offspring. There isn't any research in humans, and the significance of these findings to people, if any, is not regarded.

Ambulatory patients should be explained to to stop participating in such actions until eventually it is thought that they don't grow to be drowsy or dizzy from promethazine and codeine therapy. Pediatric patients really should be supervised to prevent opportunity harm in bike Driving or in other hazardous functions.

Promethazine and codeine need to be employed during pregnancy only if the potential reward justifies the potential possibility towards the fetus.